(searched for: (10.5155/eurjchem.4.1.58-60.678))
European Journal of Chemistry, Volume 4, pp 58-60; doi:10.5155/eurjchem.4.1.58-60.678
The study was conducted with the purpose to develop and validate a high performance liquid chromatography method with UV detector to determine ketoprofen content in tablet preparation using ethanol-phosphate buffer (pH = 6.0, 80:20, v:v). The method was validated toward parameters of accuracy, precision, linearity, selectivity, LOD and LOQ. The results obtained fulfill the validation requirement of the ketoprofen tablet in the form of LOD = 0.5302 ppm and LOQ = 1.7676 ppm.