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(searched for: doi:10.1249/*)
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Anna M. Savolainen, Anna Karmi, Heidi Immonen, Minna Soinio, Virva Saunavaara, Tam Pham, Paulina Salminen, Mika Helmiö, Jari Ovaska, Eliisa Löyttyniemi, et al.
Medicine & Science in Sports & Exercise, Volume 51, pp 278-287; doi:10.1249/MSS.0000000000001778

Abstract: Bariatric surgery is considered as an effective therapeutic strategy for weight loss in severe obesity. Remission of type 2 diabetes is often achieved after the surgery. We investigated whether increase in self-reported habitual physical activity associates with improved skeletal muscle insulin sensitivity and reduction of fat depots after bariatric surgery. We assessed self-reported habitual physical activity using Baecke questionnaire in 18 diabetic and 28 nondiabetic patients with morbid obesity (median age, 46 yr; body mass index, 42.0 kg·m−2) before and 6 months after bariatric surgery operation. Insulin-stimulated femoral muscle glucose uptake was measured using fluorodeoxyglucose positron emission tomography method during hyperinsulinemia. In addition, abdominal subcutaneous and visceral fat masses were quantified using magnetic resonance imaging and liver fat content using magnetic resonance spectroscopy. Also, serum proinflammatory cytokines were measured. Patients lost on average 22.9% of weight during the follow-up period of 6 months (P < 0.001). Self-reported habitual physical activity level increased (P = 0.017). Improvement in skeletal muscle insulin sensitivity was observed only in those patients who reported increase in their physical activity postoperatively (P = 0.018). The increase in self-reported physical activity associated with the loss of visceral fat mass (P = 0.029). Postoperative self-reported physical activity correlated also positively with postoperative hepatic insulin clearance (P = 0.02) and tended to correlate negatively with liver fat content (P = 0.076). Postoperative self-reported physical activity also correlated negatively with serum TNFα, methyl-accepting chemotaxis protein and interleukin 6 levels. Self-reported physical activity is associated with reversal of skeletal muscle insulin resistance after bariatric surgery as well as with the loss of visceral fat content and improved postoperative metabolism in bariatric surgery patients. Trial registration: Clinicaltrials.gov, NCT00793143 (SLEEVEPASS), NCT01373892 (SLEEVEPET2).
Patrick J. Highton, Fernanda R. Goltz, Naomi Martin, David J. Stensel, Alice E. Thackray, Nicolette C. Bishop
Medicine & Science in Sports & Exercise, Volume 51, pp 1935-1943; doi:10.1249/MSS.0000000000001985

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Pablo Molina-Garcia, Damian Miranda-Aparicio, Alejandro Molina-Molina, Abel Plaza-Florido, Jairo H. Migueles, Jose Mora-Gonzalez, Cristina Cadenas-Sanchez, Irene Esteban-Cornejo, Maria Rodriguez-Ayllon, Patricio Solis-Urra, et al.
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002157

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Amy A. Kirkham, Kelcey A. Bland, David S. Zucker, Joshua Bovard, Tamara Shenkier, Donald C. McKenzie, Margot K. Davis, Karen A. Gelmon, Kristin L. Campbell
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002151

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Shuen Yee Lee, Stephen F. Burns, Kenneth K.C. Ng, David J. Stensel, Liang Zhong, Frankie H.Y. Tan, Kar Ling Chia, Kai Deng Fam, Margaret M.C. Yap, Kwee Poo Yeo, et al.
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002150

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Kent W. Crossley, Doran A. Porter, Joshua Ellsworth, Tabitha Caldwell, J. Brent Feland, Ulrike Mitchell, A. Wayne Johnson, Dennis Egget, Jayson R. Gifford
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002156

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Jonna K. Van Vulpen, Maike G. Sweegers, Petra H.M. Peeters, Kerry S. Courneya, Robert U. Newton, Neil K. Aaronson, Paul B. Jacobsen, Daniel A. Galvão, Mai J. Chinapaw, Karen Steindorf, et al.
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002154

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Daniel J. Corwin, Catherine C. McDonald, Kristy B. Arbogast, Fairuz N. Mohammed, Kristina B. Metzger, Melissa R. Pfeiffer, Declan A. Patton, Colin M. Huber, Susan S. Margulies, Matthew F. Grady, et al.
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002163

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Matthew N. Cramer, Gilbert Moralez, Mu Huang, Ken Kouda, Paula Y.S. Poh, Craig G. Crandall
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002160

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Gabriella M. McLoughlin, Yang Bai, Gregory J. Welk
Medicine & Science in Sports & Exercise; doi:10.1249/mss.0000000000002159

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