Bioceramic cement in endodontic fillings: a randomized clinical trial

Abstract

Statement of the Problem: The bioceramic cements have properties that provide periradicular and root regeneration. Attributes that determine regenerative dentistry. Purpose: the objective of this study was to evaluate endodontic treatments of necrotic teeth performed with PBS HP CIMMO® cement (without gutta-percha), compared to conventional treatments, filled with gutta-percha. Materials and Method: A two-arm, double-blind, single-center, randomized, and prospective clinical trial was designed (NCT03514264). CONSORT guidelines were followed. Eighty-six patients aged 18-60 years were enrolled; only one tooth per patient was treated. Patients were treated in two sessions in Group A (gutta-percha thermoplasticization and vertical hydraulic compresssion and AH Plus® n=43) and one session in Group B (PBS HP CIMMO® n=43). The evaluation was performed one year after the treatment. Two examiners performed clinical examinations and evaluated CT images for the presence or absence of periradicular lesion. Intention-to-treat analysis was used. Results: Tomographic analyzes showed differences between the groups: group B (PBS HP CIMMO®) presented a higher number of cases with periradicular regeneration (p=0.0004). Conclusion: The results of the present study indicated the possibility of rehabilitation of necrotic teeth through endodontic filling with bioceramic (PBS HP CIMMO®), without gutta-percha, in a single session.