Two Patients Experience Same-Day Analgesic Effect of Methadone on Trigeminal Neuralgia Secondary to Malignancy: A Case Report
- 12 January 2023
- journal article
- editorial
- Published by Mary Ann Liebert Inc in Journal of Palliative Medicine
- Vol. 26 (7), 1024-1026
- https://doi.org/10.1089/jpm.2022.0436
Abstract
Trigeminal neuralgia (TN) secondary to malignancy leads to significant distress and subsequently impacts a patient's quality of life. Use of methadone as a first-line opioid analgesic in this subset of oncology patients is uncommon and is rarely initiated after traditional first-line therapies have failed. We report two patients with TN secondary to tumor burden who experienced significant analgesia within 24 hours of methadone initiation.Keywords
This publication has 11 references indexed in Scilit:
- First-line methadone for cancer pain: titration time analysisSupportive Care in Cancer, 2021
- Methadone as the Initial Long-Acting Opioid in Children with Advanced CancerJournal of Palliative Medicine, 2018
- Characterizing Treatment Utilization Patterns for Trigeminal Neuralgia in the United StatesThe Clinical Journal of Pain, 2018
- Evaluating the impact of trigeminal neuralgiaPain, 2017
- Methadone in post-herpetic neuralgia: A pilot proof-of-concept studyClinics, 2013
- Effects of Carbamazepine/Oxycodone Coadministration in the Treatment of Trigeminal NeuralgiaAnnals of Pharmacotherapy, 2011
- EFNS guidelines on the pharmacological treatment of neuropathic pain: 2010 revisionEuropean Journal of Neurology, 2010
- Differential expression of neuronal voltage-gated sodium channel mRNAs during the development of the rat trigeminal ganglionBrain Research, 2009
- Measurement of Changes in Opioid Receptor Binding in Vivo During Trigeminal Neuralgic Pain Using [11C]Diprenorphine and Positron Emission TomographyJournal of Cerebral Blood Flow & Metabolism, 1999
- Trigeminal NeuralgiaCNS Drugs, 1997