Inflammatory myofibroblastic tumor of the oral cavity
- 1 January 2019
- journal article
- review article
- Published by Medknow in Journal of Cancer Research and Therapeutics
- Vol. 15 (3), 725-728
- https://doi.org/10.4103/jcrt.jcrt_1044_16
Abstract
Inflammatory myofibroblastic tumor (IMT) is a rare tumor of unknown etiology and pathogenesis. The lesion has been recognized to occur at various sites but rarely affects the head and neck region. A 29-year-old male presented with a 13 months' history of a slow growing, painless growth in maxillary left posterior gingiva. An excisional biopsy was performed under local anesthesia. Microscopic examination revealed a compact cellular spindle cell proliferation with collagenous stroma having storiform architecture. Immunohistochemistry revealed that the tumor cells were positive for smooth muscle actin, CD-68 and negative for anaplastic lymphoma kinase. Oral IMT should be included in the differential diagnosis of localized gingival enlargement mimicking oral hyperplastic/reactive lesions.Keywords
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