Background:Many physicians in Turkey are both clinicians and researchers, and publishing their research contributes to better patient care as well as to career advancement. Objective: To identify the barriers faced by Turkish physicians to writing research papers and getting them published. Methods:Respondents were asked, through eight multiple-choice questions, about the difficulties they faced in writing research papers and in getting them published in journals. We also searched published literature for accounts of similar difficulties and answers to the question ‘What is your purpose in writing scientific publications?’ Results:A total of 18% (155 of 871) of physicians completed the questionnaire. About the difficulties faced in writing, 82 out of the 155 participants, or 57%, reported problems in finding financial support; 58 (40%), in obtaining required permissions and clearances; 65 (45%), in acquiring relevant skills, especially those related to data analysis or statistics; and 42 (29%), in language-related skills. About the difficulties in getting their papers published in journals, 85 (60%) said that they tried to overcome the difficulties by searching for appropriate solutions on the internet; 66 (47%) sought help from experienced colleagues; and 47 (33%) needed professional help in English translation and editing. Need for financial support was reported by a significantly (p = 0.04) larger proportion of associate professors or full professors (69%) than that of residents (47%) and fellows (45%). Conclusion: The main problems that Turkish physicians face in preparing scientific manuscripts were lack of financial support, inadequate knowledge of data analysis and statistics, and the paperwork involved in obtaining required approvals and permissions—problems that were common to the departments of internal medicine and of surgery. The primary motivation for writing and publishing was career advancement, especially through promotion to a higher academic rank.