While the opioid epidemic has raged across the nation, attentions lately have turned to Appalachia, where the people of the region have been hardest hit with the issue. Eric Eyre, the Pulitzer Prize winner for Investigating Reporting, weaves the tale of the battle those in southern West Virginia waged against the source of the epidemic itself. Death in Mud Lick, the culmination of nearly fifteen years of Eyre's reporting for the Charleston Gazette newspaper in Charleston, West Virginia, brings to light the full story of the state's battle against the pharmaceutical distributors of name brand drugs like Oxycontin, Lortab, and other potent opioid drugs that ravaged the people of the region. This battle, Eyre says, "set up a collision course with three of America's largest corporations" (xiv).