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TRACE ELEMENTS CONTENTS DYNAMICS IN WHOLE BLOOD IN CHILDREN WITH END STAGE RENAL DISEASE RECEIVING DIALYSIS

M. G. Prodanchuk, O. O. Makarov, B. S. Sheiman, O. G. Vasileva, G. B. Bodnar
Ukrainian Journal of Nephrology and Dialysis pp 33-38; doi:10.31450/ukrjnd.4(40).2013.05

Abstract: Homeostasis disorders in kidneys damage is accompanied by the accumulation or reduction of trace elements as a component of Chronic Kidney Disease (CKD) progression. The degree of trace elements misbalanced depends on the stage of CKD. The deep disorders are most common during renal replacement therapy (RRT), especially in children due to anatomic and physiological immaturity. Materials and methods: We investigated the 20 trace elements blood concentrations in 42 children with CKD V D depending on RRT duration used the technique of inductive coupled plasma mass-spectrometry (ICPMS). Results: There is detected significant increase of cobalt (in 3,80 times), cadmium (2,66), lead (2,44) and nickel (7,19) in patients with statistically weighty decrease in vanadium (1,49), chromium (1,62), arsenic (9,45), strontium (2,02), barium (5,29), rubidium (2,69 and zinc (1,46). It was found the increasing levels of aluminum, chromium and zinc in RRT duration enlargement (p
Keywords: Children / zinc / trace elements / chromium / chronic kidney disease / CKD / duration / RRT

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