New Search

Export article
Open Access

Immune-metabolic mechanisms of post-traumatic stress disorder and atherosclerosis

Yali Tian, Hanif Ullah, Jun Gu, Ka Li
Published: 8 February 2023

Abstract: The interaction of post-traumatic stress disorder (PTSD) and atherosclerosis (AS) increase the risk of mortality. Metabolism and immunity play important roles in the comorbidity associated with PTSD and AS. The adenosine monophosphate-activated protein kinase/mammalian target of rapamycin and phosphatidylinositol 3-kinase/Akt pathways are attractive research topics in the fields of metabolism, immunity, and autophagy. They may be effective intervention targets in the prevention and treatment of PTSD comorbidity with AS. Herein, we comprehensively review metabolic factors, including glutamate and lipid alterations, in PTSD comorbidity with AS and discuss the possible implications in the pathophysiology of the diseases.
Keywords: Post-traumatic stress disorder / atherosclerosis- / Metabolism / immune / AMPK/mTOR / PI3K/AKT

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

Share this article

Click here to see the statistics on "Frontiers in Physiology" .
References (95)
    Back to Top Top