Electrochemical Deoxygenative Thiolation of Preactivated Alcohols and Ketones
- 14 September 2021
- journal article
- research article
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 23 (19), 7524-7528
- https://doi.org/10.1021/acs.orglett.1c02738
Abstract
This work describes an electrochemically promoted nickel-catalyzed deoxygenative thiolation of alcohols and ketones under mild conditions. Excellent substrate tolerance and good chemical yields can be achieved by graphene/nickel foam electrodes in an undivided cell. Further study to gain mechanistic insight into this electrochemical cross-coupling has been carried out.Keywords
Funding Information
- National Natural Science Foundation of China (21772085, 21971107, 22071101)
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