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Determinación de las condiciones óptimas en la obtención de ácido poliláctico para la elaboración de biomateriales

Augusta Jiménez-Sánchez, Universidad de Guayaquil, Diego-Alexander Cumbe-Gordillo, Michelle-Alejandra Herrera-Cortés, Linet Hernández-Gil, Elianne Rodríguez-Larraburu, Carla-María Gutiérrez-Quiroz, Sociedad Nacional de Galápagos (Songa C.A.), Galapesca, Instituto Superior Universitario Bolivariano de Tecnología

Abstract: Introduction: Polylactic acid is an alternative to petrochemical polymers. Objective: To determine the optimal conditions for the synthesis of polylactic acid by direct polycondensation for the production of biomaterials. Materials and methods: 32 PLA studies were analyzed and 8 to specify their medical applications. Results: Start with commercial or fermented lactic acid between 25-50 mm Hg under vacuum, SnCl2/p-TsOH at 0.1-0.6% for 15-45 min with 100-300 W at 50-150°C. Conclusions: Several factors such as raw material, synthesis processes and pH influence the yield and type of polymer. PLA can be used as a biomaterial in different applications, especially in the health area.
Keywords: optimal / polylactic / polymer / biomateriales / specify / raw / óptimas / ácido / vacuum / condiciones

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