Characteristics of the Metabolic Syndrome in the Patients of IBERICAN Study (Identification of the Spanish Population at Cardiovascular and Renal Risk)
- 1 November 2017
- journal article
- research article
- Published by Mary Ann Liebert Inc in Metabolic Syndrome and Related Disorders
- Vol. 15 (9), 431-438
- https://doi.org/10.1089/met.2017.0114
Abstract
Objective: The main objective of this study is to know the prevalence and the clinical and epidemiological characteristics of patients with metabolic syndrome (MetS) and premorbid metabolic syndrome (pre-MetS) included in the Identification of the Spanish Population at Cardiovascular and Renal Risk (IBERICAN) study. Materials and Methods: The IBERICAN study is an epidemiological, multicentric observational study carried out in Primary Healthcare Centers from all over Spain, in which an open cohort of subjects with/without cardiovascular risk factors (CVRF) is constituted. The MetS was defined according to the international criterion based on the presence of at least three of the five criteria of the harmonized definition. Results: A total of 4304 patients were selected; 38.5% patients (95% confidence interval 37.0–40.0) met the MetS criteria. In both groups (MetS and pre-MetS), patients were older (62.3 ± 12.1 vs. 54.4 ± 15.2, P < 0.001). The CVRF analyzed were more frequent in patients with MetS: hypertension (HT) (71.1% vs. 33.0%, P < 0.001), dyslipidemia (65.8% vs. 40.2%, P < 0.001), diabetes mellitus (DM) (38.2% vs. 6.4%, P < 0.001), and obesity (54.8% vs. 21.7%, P < 0.001), and all the cardiovascular diseases (CVDs) analyzed were more prevalent in these patients: stroke (5.1% vs. 3.6%, P = 0.013), heart failure (5.1% vs. 1.6%, P < 0.001), ischemic heart disease (9.8% vs. 5.8%, P < 0.001), and peripheral arterial disease (6.8% vs. 3.7%, P < 0.001). We observed that patients with DM were 6.36 times more likely to present MetS; patients with obesity, 3.81 times; and patients with HT, 2.66 times. Conclusion: Patients with MetS and with pre-MetS presented higher CVRF and increased associated renal and CVD. The prognostic value of these findings must be analyzed in the longitudinal follow-up of the IBERICAN cohort.Keywords
This publication has 22 references indexed in Scilit:
- 2016 ESC/EAS Guidelines for the Management of DyslipidaemiasEuropean Heart Journal, 2016
- The clinical value of metabolic syndrome and risks of cardiometabolic events and mortality in the elderly: the Rotterdam studyCardiovascular Diabetology, 2016
- Magnitud y manejo del síndrome metabólico en España en 2008-2010: Estudio ENRICARevista Espanola de Cardiologia, 2014
- 2013 ESH/ESC Guidelines for the management of arterial hypertensionEuropean Heart Journal, 2013
- Prevalence of the metabolic syndrome in Spain using regional cutoff points for waist circumference: the di@bet.es studyActa Diabetologica, 2013
- Clinical usefulness of the metabolic syndrome for the risk of coronary heart disease does not exceed the sum of its individual components in older men and women. The Three-City (3C) StudyHeart, 2012
- Síndrome metabólico en España: prevalencia y riesgo coronario asociado a la definición armonizada y a la propuesta por la OMS. Estudio DARIOSRevista Española de Cardiología (English Edition), 2012
- The Metabolic Syndrome and Cardiovascular Risk: A Systematic Review and Meta-AnalysisJournal of Invasive Cardiology, 2010
- The metabolic syndrome: useful concept or clinical tool? Report of a WHO Expert ConsultationDiabetologia, 2009
- Harmonizing the Metabolic SyndromeJournal of the American College of Cardiology, 2009