Protein C in a patient with portal vein thrombosis in liver transplantation
Open Access
- 21 June 2021
- journal article
- Published by IPO Association of Transplantologists in Transplantologiya
- Vol. 13 (2), 151-157
- https://doi.org/10.23873/2074-0506-2021-13-2-151-157
Abstract
Background. The problem of thromboses, including those associated with impaired hemostasis system, is relevant in orthotopic liver transplantation.Aim. To present the experience of intraoperative use of protein C during orthotopic liver transplantation in a patient with a high risk of recurrent portal vein thrombosis.Results. During orthotopic liver transplantation in a patient with a high risk of recurrent portal vein thrombosis, the intraoperative administration of the protein C preparation at a dosage of 500 IU contributed to the increase in plasma level of protein C by 48%. In the post-transplant period, recurrent portal vein thrombosis was not observed. Conclusion. Intraoperative administration of protein C in combination with basic therapy for orthotopic liver transplantation helps to prevent recurrent portal vein thrombosis.Keywords
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