Outbreak analysis with a logistic growth model shows COVID-19 suppression dynamics in China
Open Access
- 29 June 2020
- journal article
- research article
- Published by Public Library of Science (PLoS) in PLOS ONE
- Vol. 15 (6), e0235247
- https://doi.org/10.1371/journal.pone.0235247
Abstract
China reported a major outbreak of a novel coronavirus, SARS-CoV2, from mid-January till mid-March 2020. We review the epidemic virus growth and decline curves in China using a phenomenological logistic growth model to summarize the outbreak dynamics using three parameters that characterize the epidemic’s timing, rate and peak. During the initial phase, the number of virus cases doubled every 2.7 days (range 2.2–4.4 across provinces). The rate of increase in the number of reported cases peaked approximately 10 days after suppression measures were started on 23–25 January 2020. The peak in the number of reported sick cases occurred on average 18 days after the start of suppression measures. From the time of starting measures till the peak, the number of cases increased by a factor 39 in the province Hubei, and by a factor 9.5 for all of China (range: 6.2–20.4 in the other provinces). Complete suppression took up to 2 months (range: 23-57d.), during which period severe restrictions, social distancing measures, testing and isolation of cases were in place. The suppression of the disease in China has been successful, demonstrating that suppression is a viable strategy to contain SARS-CoV2.This publication has 22 references indexed in Scilit:
- The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and ApplicationAnnals of Internal Medicine, 2020
- Characteristics of and Important Lessons From the Coronavirus Disease 2019 (COVID-19) Outbreak in ChinaJAMA, 2020
- How will country-based mitigation measures influence the course of the COVID-19 epidemic?The Lancet, 2020
- Can China's COVID-19 strategy work elsewhere?Science, 2020
- Evolving Epidemiology and Impact of Non-pharmaceutical Interventions on the Outbreak of Coronavirus Disease 2019 in Wuhan, ChinaPublished by Cold Spring Harbor Laboratory ,2020
- Feasibility of controlling COVID-19 outbreaks by isolation of cases and contactsThe Lancet. Global Health, 2020
- Open-source analytics tools for studying the COVID-19 coronavirus outbreakPublished by Cold Spring Harbor Laboratory ,2020
- Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling studyThe Lancet, 2020
- Mathematical Models in BiologyPublished by Society for Industrial & Applied Mathematics (SIAM) ,2005
- Elements of Mathematical EcologyPublished by Cambridge University Press (CUP) ,2001