Effect of chronic kidney disease on total knee arthroplasty outcomes: a meta-analysis of matched control studies
Open Access
- 2 July 2021
- journal article
- review article
- Published by Springer Science and Business Media LLC in Arthroplasty
- Vol. 3 (1), 1-8
- https://doi.org/10.1186/s42836-021-00078-4
Abstract
The purpose of this meta-analysis was to review the current evidence in the literature to find out whether the coexisting chronic kidney disease affected infection, revision, transfusion, readmission, mortality, and the length of hospital stay after total knee arthroplasty. Medline, PubMed, Embase, and the Cochrane Library were searched from their dates of inception to June 30, 2020. The primary outcomes were postoperative infection, revision, and mortality. The secondary outcomes were transfusion, the length of hospital stay, and readmission. A P value of < 0.05 was deemed to be statistically significant. A total of 881 articles were identified, and 7 articles that met the inclusion criteria were identified to be eligible. The most important finding of our study was that the chronic kidney disease was associated with increased postoperative transfusion (P < 0.05) and mortality (P < 0.05). Meanwhile, the patients with chronic kidney disease were associated with a higher readmission rate, compared to the patients without chronic kidney disease (P < 0.05). However, chronic kidney disease was not associated with high risks for infection (P > 0.05), revision surgeries (P > 0.05), and a prolonged hospital stay (P > 0.05). After total knee arthroplasty, the patients with coexisting chronic kidney disease carry higher risks of transfusion, mortality, and readmission. However, the chronic kidney disease may not be associated with the risk of infection or revision, nor the duration of hospitalization.Keywords
This publication has 33 references indexed in Scilit:
- Predictors of perioperative blood transfusions in patients with chronic kidney disease undergoing elective knee and hip arthroplastyNephrology, 2014
- A retrospective study of cytomegalovirus pneumonia in renal transplant patientsExperimental and Therapeutic Medicine, 2014
- Total knee arthroplasty in patients with dialysis: Early complications and mortalityBiomedical Journal, 2014
- Can total knee arthroplasty be safely performed in patients with chronic renal disease?Acta Orthopaedica, 2013
- The comparative efficacies of intra-articular and IV tranexamic acid for reducing blood loss during total knee arthroplastyKnee Surgery, Sports Traumatology, Arthroscopy, 2012
- Patient-Related Risk Factors for Periprosthetic Joint Infection and Postoperative Mortality Following Total Hip Arthroplasty in Medicare PatientsJournal of Bone and Joint Surgery, 2012
- Patient-related Risk Factors for Postoperative Mortality and Periprosthetic Joint Infection in Medicare Patients Undergoing TKAClinical Orthopaedics and Related Research, 2012
- Chronic Kidney Disease and Postoperative Morbidity After Elective Orthopedic SurgeryAnesthesia & Analgesia, 2011
- Rates of infection and revision in patients with renal disease undergoing total knee replacement in ScotlandThe Journal of Bone and Joint Surgery. British volume, 2010
- Simultaneous rupture of the quadriceps tendon and contralateralpatellar tendon in a patient with chronic renal failureJournal of Orthopaedic Science, 2005