β‐Cyclodextrin: An Efficient Supramolecular Catalyst for the Synthesis of Pyranoquinolines Derivatives under Ultrasonic Irradiation in Water

Abstract

A newer, convenient and efficient approach has been designed for the diverse synthesis of 2-amino-4H-pyranoquinolines and achieved by a one-pot three-component reaction of aromatic aldehydes with ethyl cyanoacetate/malononitrile and 8-hydroxyquinoline catalyzed by β-cyclodextrin as a reusable supramolecular catalyst in an aqueous medium under ultrasound irradiation. Target products were synthesized in a tandem process, which meets their requirements of pharmaceutical chemistry.