Persistently Elevated mTOR Complex 1-S6 Kinase 1 Disrupts DARPP-32–Dependent D1 Dopamine Receptor Signaling and Behaviors
- 27 October 2020
- journal article
- research article
- Published by Elsevier BV in Biological Psychiatry
- Vol. 89 (11), 1058-1072
- https://doi.org/10.1016/j.biopsych.2020.10.012
Abstract
No abstract availableFunding Information
- National Institutes of Health
This publication has 57 references indexed in Scilit:
- Anhedonia requires MC4R-mediated synaptic adaptations in nucleus accumbensNature, 2012
- Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant miceNature, 2012
- Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complexNeurobiology of Disease, 2012
- Mutations causing syndromic autism define an axis of synaptic pathophysiologyNature, 2011
- Shank3 mutant mice display autistic-like behaviours and striatal dysfunctionNature, 2011
- Rheb1 Is Required for mTORC1 and Myelination in Postnatal Brain DevelopmentDevelopmental Cell, 2011
- Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugsNature Neuroscience, 2008
- Reversal of learning deficits in a Tsc2+/− mouse model of tuberous sclerosisNature Medicine, 2008
- A phosphatase cascade by which rewarding stimuli control nucleosomal responseNature, 2008
- Protein kinase A activates protein phosphatase 2A by phosphorylation of the B56δ subunitProceedings of the National Academy of Sciences of the United States of America, 2007