Osteoclastic giant cell variant of urothelial carcinoma in a COVID- positive patient: A rare variant in an unusual circumstances
Open Access
- 12 April 2021
- journal article
- Published by Heighten Science Publications Corporation in Archives of Case Reports
- Vol. 5 (1), 009-011
- https://doi.org/10.29328/journal.acr.1001047
Abstract
Bladder carcinomas have a great propensity for divergent differentiation with more that 90% being Transitional cell carcinoma. Several histological variants have been have described so far; they are not only morphologically unique but also have significant prognostic and therapeutic differences making their timely identification of paramount importance. Osteoclastic giant cell variant of urothelial carcinoma is very rare type with controversial management. Studies from China have documented higher incidence and severity of illness in COVID-19 positive cancer patients. We report an unusual case of Osteoclastic giant cell variant of urothelial carcinoma in a 63 yrs old male patient associated with simultaneous COVID-19 infection.Keywords
This publication has 12 references indexed in Scilit:
- Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus–Infected Pneumonia in Wuhan, ChinaJAMA, 2020
- Cancer patients in SARS-CoV-2 infection: a nationwide analysis in ChinaThe Lancet Oncology, 2020
- Osteoclast-type giant cell carcinoma of the urinary bladder: An unusual and aggressive variant of urothelial carcinomaUrology Case Reports, 2018
- Recently described and unusual variants of urothelial carcinoma of the urinary bladderPathology, 2012
- Gallbladder carcinoma with osteoclast-like giant cellsThe Esophagus, 2006
- Osteoclast-rich undifferentiated carcinomas of the urinary tractLaboratory Investigation, 2006
- A population-based study of immunohistochemical detection of p53 alteration in bladder cancerBritish Journal of Cancer, 2004
- Secondary malignant giant‐cell tumour of bone: molecular abnormalities of p53 and H‐ras gene correlated with malignant transformationHistopathology, 2001
- Immunophenotype of High-Grade Prostatic Adenocarcinoma and Urothelial CarcinomaLaboratory Investigation, 2000
- Giant cell tumor of the kidneyVirchows Archiv A Pathological Anatomy and Histopathology, 1983