Emergence of the novel SARS-CoV-2 lineage VUI-NP13L and massive spread of P.2 in South Brazil
Open Access
- 1 January 2021
- journal article
- research article
- Published by Taylor & Francis Ltd in Emerging Microbes & Infections
- Vol. 10 (1), 1431-1440
- https://doi.org/10.1080/22221751.2021.1949948
Abstract
In this study, we analyzed 340 whole genomes of SARS-CoV-2, which were sampled between April and November 2020 in 33 cities of Rio Grande do Sul, South Brazil. We demonstrated the circulation of two novel emergent lineages, VUI-NP13L and VUI-NP13L-like, and five major lineages that had already been assigned (B.1.1.33, B.1.1.28, P.2, B.1.91, B.1.195). P.2 and VUI-NP13L demonstrated a massive spread in October 2020. Constant and consistent genomic surveillance is crucial to identify newly emerging SARS-CoV-2 lineages in Brazil and to guide decision making in the Brazilian Public Healthcare System.Keywords
Funding Information
- Hospital Moinhos de Vento (25000.012591/2021-21)
This publication has 49 references indexed in Scilit:
- Virus population dynamics during infectionCurrent Opinion in Virology, 2017
- Extensive Positive Selection Drives the Evolution of Nonstructural Proteins in Lineage C BetacoronavirusesJournal of Virology, 2016
- Coronavirus NSP6 restricts autophagosome expansionAutophagy, 2014
- The Newick utilities: high-throughput phylogenetic tree processing in the Unix shellBioinformatics, 2010
- Fast and accurate long-read alignment with Burrows–Wheeler transformBioinformatics, 2010
- The Sequence Alignment/Map format and SAMtoolsBioinformatics, 2009
- Fast and accurate short read alignment with Burrows–Wheeler transformBioinformatics, 2009
- SARS coronavirus replicase proteins in pathogenesisVirus Research, 2008
- Characterization of the 3a Protein of SARS-associated Coronavirus in Infected Vero E6 Cells and SARS PatientsJournal of Molecular Biology, 2004
- Unique and Conserved Features of Genome and Proteome of SARS-coronavirus, an Early Split-off From the Coronavirus Group 2 LineageJournal of Molecular Biology, 2003