2-Nnitrobenzaldehyde is an important organic intermediate, which is widely used in organic syn-thesis and pharmaceutical fields. 2-Nitrobenzaldehyde was synthesized from N,N’-dimethylformamide dimethyl acetal (DMFDMA) by condensation oxidation. The isolated prod-uct was analyzed by 1H NMR, 13C NMR and FT-IR spectroscopic methods. The total yield was 88.03%, and the purity was as high as 99.07% (HPLC). The synthetic production process has the advantages of low economic cost, high yield and low environmental pollution, and has obvious advantages over the traditional process.