Multiple tuberous xanthomas diagnosed on fine-needle aspiration cytology – Report of a rare case
Open Access
- 7 June 2022
- journal article
- research article
- Published by Scientific Scholar in Cytojournal
- Vol. 19, 37
- https://doi.org/10.25259/cytojournal_86_2020
Abstract
Xanthomas are papulonodular skin lesions present in lipoprotein metabolism disorders, which result in cholesterol deposits in subcutaneous tissue, tendons, ligaments, periosteum, etc. A 28-year-old male presented with multiple soft-tissue swellings, prominently over joints. Fine-needle aspiration (FNA) from multiple sites had similar appearance with foamy histocytes and giant cells. We describe an unusual case of tendinous and tuberous xanthoma diagnosed by cytology. Acquaintance with FNA cytology findings in xanthomas can help to avoid the need of surgical biopsy, as xanthomas can regress on medical therapy alone.Keywords
This publication has 10 references indexed in Scilit:
- Multiple tuberous and tendinous xanthomas diagnosed on fine‐needle aspiration cytology—report of a rare caseDiagnostic Cytopathology, 2019
- Cutaneous xanthomas in a young child: Familial hypercholesterolemiaIndian Dermatology Online Journal, 2017
- Multiple large xanthomas: A case reportOncology Letters, 2016
- An Unusual Case of Multiple Tendinous Xanthomas Involving the Extremities and the EarsCase Reports in Dermatology, 2015
- Giant tuberous xanthomas in a case of type IIA hypercholesterolemiaJournal of Cutaneous and Aesthetic Surgery, 2012
- Cytomorphological diagnosis of tendinous xanthomatosis: A case reportDiagnostic Cytopathology, 2009
- Tuberous xanthomas in type IIA hyperlipoproteinemia.2007
- Cerebrotendinous XanthomatosisActa Cytologica, 2007
- Familial Hypercholesterolemia and Coronary Heart Disease: A HuGE Association ReviewAmerican Journal of Epidemiology, 2004
- The transfer of proteins and lipids from plasma to lymph in the leg of the normal and hypercholesterolaemic rabbitJournal Of Physiology-London, 1961