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The SARS-CoV-2 receptor-binding domain preferentially recognizes blood group A

Shang-Chuen Wu, Connie M. Arthur, Jianmei Wang, Hans Verkerke, Cassandra D. Josephson, Daniel Kalman, John D. Roback, Richard D. Cummings,
Published: 3 March 2021

Abstract: Key Points The RBD of SARS-CoV-2 shares sequence similarity with an ancient lectin family known to bind blood group antigens. SARS-CoV-2 RBD binds the blood group A expressed on respiratory epithelial cells, directly linking blood group A and SARS-CoV-2.
Keywords: lectin / ancient / directly / SARS CoV / antigens / epithelial / recognizes / preferentially / blood group

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