Computer‐aided analysis of fluorescein angiograms using colour leakage maps
Open Access
- 1 June 2015
- journal article
- research article
- Published by Institution of Engineering and Technology (IET) in IET Image Processing
- Vol. 9 (6), 486-495
- https://doi.org/10.1049/iet-ipr.2013.0672
Abstract
Fundus fluorescein angiography (FFA) is a standard screening and diagnosis technique for several retinal diseases. The analysis of FFA images is performed qualitatively by skilled observers, and thus is vulnerable to inter- and intra-observer variability. In this study, the authors present a method for computer-aided analysis of FFA images. The method is based on generating quantitative colour fluorescein leakage maps (FLM) that mimic the thickness maps generated by the optical coherence tomography (OCT). Results from 64 patients show strong correlation between the FLM and OCT thickness maps (r = 0.8). The method was found to be reproducible and robust to variability in the image acquisition times.Keywords
This publication has 20 references indexed in Scilit:
- Automatic Detection of Exudates in Diabetic Retinopathy ImagesJournal of Computer Science, 2012
- Exudates segmentation using inverse surface adaptive thresholdingMeasurement, 2012
- Automatic Characterization of Classic Choroidal Neovascularization by Using AdaBoost for Supervised LearningInvestigative Ophthalmology & Visual Science, 2011
- Medical RetinaPublished by Springer Science and Business Media LLC ,2010
- Automatic detection of diabetic retinopathy exudates from non-dilated retinal images using mathematical morphology methodsComputerized Medical Imaging and Graphics, 2008
- Dynamic and Quantitative Analysis of Choroidal Neovascularization by Fluorescein AngiographyInvestigative Ophthalmology & Visual Science, 2006
- A contribution of image processing to the diagnosis of diabetic retinopathy-detection of exudates in color fundus images of the human retinaIEEE Transactions on Medical Imaging, 2002
- Optical Coherence Tomography: An Emerging Technology for Biomedical Imaging and Optical BiopsyNeoplasia, 2000
- Quantifying changes in retinal circulation: the generation of parametric images from fluorescein angiogramsPhysiological Measurement, 1998
- Topography of diabetic macular edema with optical coherence tomographyOphthalmology, 1998