COX PROPORTIONAL HAZARD REGRESSION SURVIVAL ANALYSIS FOR TYPE 2 DIABETES MELITUS

Abstract

One of the most widely used methods of survival analysis is Cox proportional hazard regression. It is a semiparametric regression used to investigate the effects of a number of variables on the dependent variable based on survival time. Using the Cox proportional hazard regression method, this study aims to estimate the factors that influence the survival of patients with type 2 diabetes mellitus. The estimated parameter values, as well as the Cox Regression equation model, were also investigated. A total of 1293 diabetic patients with type 2 diabetes were studied, with data taken from medical records at PKU Muhammadiyah Hospital in Yogyakarta, Indonesia. These variables have regression coefficients of 1.36, 1.59, -0.63, 0.11, and 0.51, respectively. Furthermore, the results showed the hazard ratio for female patients was 1.16 times male patients. Patients on insulin treatment had a 4.92-fold higher risk of death than those on other therapy profiles. Patients with normal blood sugar levels (GDS 140 mg/dl) had a 1.12 times higher risk of death than those with other blood glucose levels. Type 2 diabetes mellitus is a challenge for many Indonesians, in addition to being a deadly condition that was initially difficult to diagnose. As a result, patient survival analysis is needed to reduce the patient's risk of death.