Selective iodination of 2-acetyl-1-naphthol using iodine and iodic acid under solvent-free grinding technique
Open Access
- 30 September 2012
- journal article
- Published by European Journal of Chemistry in European Journal of Chemistry
- Vol. 3 (3), 314-315
- https://doi.org/10.5155/eurjchem.3.3.314-315.641
Abstract
Selective electrophilic iodination of 2-acetyl-1-naphthol was achieved using iodine and iodic acid in combination with grinding at room temperature under solvent-free conditions to yield 1-(1-hydroxy-4-iodo-naphthalen-2-yl)-ethanone. Grinding mode of reactions has not only of interest from economical point of view, in many cases they also offer considerable advantages in terms of yield, mild reaction conditions, selectivity and simplicity of reaction procedure.Keywords
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