Study of antimicrobial action of chitosan and biologically active compositions based on it

Abstract

Due to the large number of functional groups in chitosan is provide the possibility of formation bonds with chemical compounds, which allows you to create polymeric complexes with new physicochemical properties and biological activity. Therefore, chitosan is widely used as a biopolymeric carrier of degradable preparation of different orientation, which ensures their effective and prolonged action. Compositions of chitosan with natural biopreservatives, which allow to obtain promising plant protection products and agricultural products, deserve special attention. Recent developments, as well as the need for safe, practical and effective food preservatives have aroused increased interest in substances such as sorbate and its combined use with chitosan. In recent decades, sorbate and chitosan have been tested and widely used in the storage of various foods around the world. The issues of adaptogenic action, antimicrobial activity of chitosan in combination with biologically active components remain little studied in Ukraine. Given the global trend towards a gradual transition to organic production, the study of the mechanisms of action of chitosan and its compounds with organic acids is a promising area of research in the control of pathogenic microorganisms for storage of fruits and vegetables. The aim of the study was to study the effectiveness of the integrated use of chitosan with sorbic acid against phytopathogenic microorganisms. The research used methods generally accepted in microbiology and phytopathology. Specificity of antimicrobial activity and prolongation of action of chitosan, sorbic acid and their mixture with respect to different isolates and strains of phytopathogenic microorganisms has been established. The bacteriostatic effect of a mixture of chitosan and sorbic acid in the variant with bacterial isolates, which was observed during 5 days was investigated. The composition of chitosan and sorbic acid contributed to the inhibition of mycelial growth of isolates of pathogens of the genera Fusarium and Alternaria.