Helical Computer Assisted Tomography in Pulmonary Hypertension Complicating Left-to-Right Shunts
- 1 January 2001
- journal article
- Published by Japanese Circulation Society in Japanese Circulation Journal
- Vol. 65 (3), 188-192
- https://doi.org/10.1253/jcj.65.188
Abstract
The present study analyzed the helical computer-assisted tomography (CAT) findings in 30 patients with pulmonary hypertension (PH) associated with left-to-right shunts; specifically, ventricular septal defect, 23; atrioventricular septal defect, 6; patent ductus arteriosus, 1. Eight patients had 21 trisomy. Age ranged from 1 to 18 (mean, 4.1) months, and body weight ranged from 2.6 to 10.7 (mean, 4.9) kg. In all patients, the chest CAT revealed patchy areas of high and low attenuation (mosaic pattern) and regional atelectasis in the lung fields. The volume of low attenuated lesions and of atelectasis, and the total lung volume were derived from integration of areas measured on the CAT image. The ratios of low attenuated lesion/total lung volume (Lo), volume of atelectasis/ total lung volume (Ate) and low attenuated lesion and volume of atelectasis/total lung volume (Lo&Ate) were compared with hemodynamic parameters measured at cardiac catheterization. The pulmonary to systemic resistance ratio correlated with Lo (r=0.61, p<0.01) and Lo&Ate (r=0.69, p<0.01), whereas the pulmonary vascular resistance correlated with Ate (r=0.53, p<0.01). Lo, Ate and Lo&Ate in the chest CAT are reliable parameters that can be used to estimate pulmonary vascular resistance in patients with PH associated with left-to-right shunts.Keywords
This publication has 37 references indexed in Scilit:
- High-resolution CT of pediatric lung disease: imaging findings.American Journal of Roentgenology, 1997
- Diffuse pulmonary disease in children: high-resolution CT findings.American Journal of Roentgenology, 1996
- CT mosaic pattern of lung attenuation: distinguishing different causes.American Journal of Roentgenology, 1995
- Regional alterations in lung ventilation in end-stage primary pulmonary hypertension: correlation between CT and scintigraphy.American Journal of Roentgenology, 1995
- Noninvasive estimation of pulmonary artery pressureThe Journal of Pediatrics, 1989
- Noninvasive diagnosis of pulmonary arterial hypertension in chronic obstructive pulmonary disease: Right ventricular ejection fraction at restThe American Journal of Cardiology, 1984
- Doppler echocardiographic prediction of pulmonary arterial hypertension in congenital heart diseaseThe American Journal of Cardiology, 1984
- Noninvasive evaluation of pulmonary hypertension by a pulsed Doppler technique.Journal of the American College of Cardiology, 1983
- Noninvasive detection of pulmonary hypertension in patent ductus arteriosus by pulsed Doppler echocardiography.Journal of the American College of Cardiology, 1979
- Echocardiographic Evaluation of Pulmonary HypertensionJournal of the American College of Cardiology, 1974