Use of Retinal Angiography and MRI in the Diagnosis of Giant Cell Arteritis With Early Ophthalmic Manifestations
- 14 January 2022
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Journal of Neuro-Ophthalmology
- Vol. 42 (2), 218-225
- https://doi.org/10.1097/wno.0000000000001517
Abstract
Background: Giant cell arteritis (GCA) is a vasculitis often revealed by visual signs. Diagnosis is challenging and urgent. Retinal angiography (RA) and MRI allow effective diagnosis. We compared those and proposed an imaging-based approach to diagnose GCA in ophthalmological practice. Methods: We conducted a retrospective study based on the data collected from patients suspected to have GCA on ophthalmological findings. Fluorescein (FA) and indocyanine green (ICG) RAs and MRI were performed and compared with final diagnosis. Results: Among the 41 patients included, 25 were diagnosed with GCA. Sensitivities and specificities of FA and ICG were not different. MRI showed a higher sensitivity and specificity. The approach consisting in performing RA followed by MRI provided a better accuracy. Conclusion: Our study shows that RA can be supplemented by MRI in a specialized center to provide the most accurate diagnosis in GCA revealed by visual signs.Keywords
This publication has 41 references indexed in Scilit:
- Comparison of duplex sonography and high‐resolution magnetic resonance imaging in the diagnosis of giant cell (temporal) arteritisArthritis & Rheumatism, 2008
- Diagnostic Value of High-Resolution MR Imaging in Giant Cell ArteritisAmerican Journal of Neuroradiology, 2007
- Giant Cell (Temporal) Arteritis: An Overview and UpdateSurvey of Ophthalmology, 2005
- Poor Prognosis of Visual Outcome after Visual Loss from Giant Cell ArteritisOphthalmology, 2005
- High-Resolution MRI in Giant Cell Arteritis: Imaging of the Wall of the Superficial Temporal ArteryAmerican Journal of Roentgenology, 2005
- Magnetic resonance imaging depicts mural inflammation of the temporal artery in giant cell arteritisArthritis & Rheumatism, 2004
- Polymyalgia Rheumatica and Giant-Cell ArteritisThe New England Journal of Medicine, 2002
- Epidemiology of giant-cell arteritis.Cleveland Clinic Journal of Medicine, 2002
- The American College of Rheumatology 1990 criteria for the classification of giant cell arteritisArthritis & Rheumatism, 1990
- L'artérite temporale de Horton Etude anatomopathologique en microscopie optique: A propos de 123 biopsies temporalesLa Revue de Médecine Interne, 1982