Methodological approaches of studying the distance learning process of students in higher education institutions are evolving alongside changes that occur in the educational system and in the global space. Therefore, the systematisation of theoretical, methodological and practical factors on which the modern methodology of distance learning is based makes it possible to form new opportunities for the education system in the direction of its modernisation. One of the components is communicative competence, that is, the ability to perceive and (re)produce the information in a foreign language in accordance with the conditions of speech communication. The purpose of the study is to characterise modern interactive methods of distance learning for the organisation and management of students’ educational activities. To achieve this goal, theoretical research methods were used: analysis, systematisation, substantiation of the conceptual apparatus of the study; the formulation of its conceptual provisions and conclusions; analysis of pedagogical documentation, content analysis of curricula and methodological support of the educational process to determine the possibilities of using educational IT-technologies in distance learning. The peculiarities of the innovative technologies usage while studying foreign languages and the theoretical and methodological foundations of Physical Culture and Sports are characterised. Distance learning of different disciplines should be included in the curricula. Several innovative forms of language “warm-up” are proposed. Modern educational WEB-technologies are studied, which allows us to expand the methodological components of distance learning in higher education institutions. The most effective distance learning means in higher education institutions has been established. The application of the Case method, the interactive «science brain storm» technology, the online versions of AWWAPP and RealtimeBoard, the use of the PRES formula and the Flipped classroom methodology has been analysed. For blended learning, it is proposed to use a traditional textbook in combination with interactive online tasks – Blended Learning – using the online tool MyEnglishLab. An important aspect is that during practical classes, the Zoom software is used for fine differentiation and accurate identification of textual material. The applied innovative teaching methods, combining new and effective methods of the educational process (knowledge generation, transfer and accumulation), will contribute to the intensification and modernization of education, as a result of which the synthesis of students’ certain competencies is achieved.