Type VII Aplasia Cutis Congenita in Neonates Related to Maternal HBV Infection? Case Report and Literature Review
Open Access
- 1 February 2023
- journal article
- review article
- Published by Taylor & Francis Ltd in Clinical, Cosmetic and Investigational Dermatology
- Vol. ume 16, 499-504
- https://doi.org/10.2147/ccid.s396071
Abstract
Aplasia cutis congenita (ACC) is a rare disease with an unclear pathogenic mechanism. ACC has been suggested to result from the disrupted development or degeneration of skin in the uterus. This study describes two cases that may have underlying pathogenic cause that have not been previously reported. Two neonates who were admitted to the neonatal intensive care unit due to “skin lesions on the limbs” without other deformities or complications were diagnosed with type VII ACC by dermatologist. The mothers showed positivity for hepatitis B virus (HBV) surface antigen and elevated level of HBV DNA copies, which may be related to ACC. But this association could be a coincidence. Both neonates were treated with antibacterial dressings and achieved satisfactory healing.Keywords
This publication has 30 references indexed in Scilit:
- Aplasia cutis congenita of the scalp- what are the steps to be followed? Case report and review of the literatureAnais Brasileiros de Dermatologia, 2015
- Congenital skin aplasia on the lower limb in a premature infant with ELBW - case reportItalian Journal of Pediatrics, 2014
- Study of the relationship in pregnant women between hepatitis B markers and a placenta positive for hepatitis B surface antigenjpme, 2014
- Coexistence of aplasia cutis congenita, faun tail nevus and fetus papyraceusJournal of Dermatological Case Reports, 2013
- BMS1 Is Mutated in Aplasia Cutis CongenitaPLoS Genetics, 2013
- Type V Aplasia Cutis Congenita: Case Report, Review of the Literature, and Proposed Treatment AlgorithmPediatric Dermatology, 2012
- Aplasia cutis congenita due to methimazol exposure within the first trimester of pregnancy: case reportjpme, 2011
- Aplasia cutis congenita. A case of scalp defect repair using two opposing bipedicled local flapsJournal of Plastic, Reconstructive & Aesthetic Surgery, 2010
- Histopathological examination of the placenta: key issues for pathologists and obstetriciansPathology, 2008
- Aplasia cutis congenita: A clinical review and proposal for classificationJournal of the American Academy of Dermatology, 1986