Recent Advances in Detection of Ochratoxin-A
Open Access
- 1 January 2013
- journal article
- Published by Scientific Research Publishing, Inc. in Open Journal of Applied Biosensor
- Vol. 02 (01), 1-11
- https://doi.org/10.4236/ojab.2013.21001
Abstract
Ochratoxin-A[7-(L-β-phenylalanylcarbonyl)-carboxyl-5-chloro-8-hydroxy-3,4-dihydro-3R-methyl-isocumarin, OTA] is a common food contaminant mycotoxin that enters the human body through the consumption of improperly stored food products. Upon ingestion, it leads to immuno-suppression and immuno-toxicity. OTA has been known to produce nephrotoxic, teratogenic, and carcinogenic activity (via oxidative DNA damage) in several species. This review introduces potentials of electrochemical biosensor to provide breakthroughs in OTA detection through improved selectivity and sensitivity and also the current approaches for detecting OTA in food products.Keywords
This publication has 87 references indexed in Scilit:
- Novel nanobiotechnological concepts in electrochemical biosensors for the analysis of toxinsThe Analyst, 2012
- Ochratoxin A Detection by an Immunosensor Using Impedance Spectroscopy Coupled with Quartz Crystal MicrobalanceSensor Letters, 2011
- Development of a colloidal gold strip for rapid detection of ochratoxin A with mimotope peptideFood Control, 2009
- HPLC determination of ochratoxin A in high consumption Tunisian foodsFood Control, 2009
- ELISA and HPLC analysis of ochratoxin A in red wines of CroatiaFood Control, 2009
- Natural occurrence of ochratoxin A in Tunisian cerealsFood Control, 2009
- Natural occurrence of ochratoxin A in dried figsAnalytica Chimica Acta, 2008
- Prospects of Nanomaterials in BiosensorsAnalytical Letters, 2008
- Recent advances in nanotechnologyJournal of the American Academy of Dermatology, 2007
- Toxicokinetics and toxicodynamics of ochratoxin A, an updateChemico-Biological Interactions, 2006