The Accuracy of Tidal Volume Measured With a Smart Shirt During Tasks of Daily Living in Healthy Subjects: Cross-sectional Study

Abstract

Journal of Medical Internet Research - International Scientific Journal for Medical Research, Information and Communication on the Internet #Preprint #PeerReviewMe: Warning: This is a unreviewed preprint. Readers are warned that the document has not been peer-reviewed by expert/patient reviewers or an academic editor, may contain misleading claims, and is likely to undergo changes before final publication, if accepted, or may have been rejected/withdrawn. Readers with interest and expertise are encouraged to sign up as peer-reviewer, if the paper is within an open peer-review period. Please cite this preprint only for review purposes or for grant applications and CVs (if you are the author). Background: The Hexoskin smart shirt (HX) is a shirt measuring continuously and objectively and could be a potential telemonitoring system. Objective: The main focus is to determine the accuracy of the calibrated HX to measure tidal volumes (TV) in comparison to spirometry (SPIRO) in various tasks. Methods: TV of fifteen healthy subjects were measured in 7 tasks with SPIRO and HX. These tasks were performed in two sessions, between sessions all equipment was removed. A one-time spirometer-based calibration per task was determined in session 1 and applied to the corresponding task in both sessions. Bland-Altman analysis was used to determine the agreement between TV measured with HX and SPIRO. A priori we determined the bias had to be less than ±5% with LOA less than ±15%. Lung volumes were measured and should have LOA less than ±0.150 L. Results: In the first session, all tasks had a median bias within the criteria (±0.6%). In the second session, biases were ±8.9%, only two tasks met the criteria. In both sessions, LOA were within criteria in six out of seven tasks (±14.7%). LOA of lung volumes were > 0.150 L. Conclusions: HX is able to correctly measure TV in healthy subjects in various tasks. However, after reapplication of the equipment, calibration factors cannot be reused to obtain results within the determined boundaries. Clinical Trial: NTR7130 (Dutch trial registration system)