The experiment entitled “Effect of Organic Manures and inorganic Fertilizers on Growth, Yield, Quality and Economics of Broccoli (Brassica oleracea var. italica) cv. Paraiso” was conducted during Rabi season of the year 2020-2021 on experimental farm of Department of Horticulture, AKS University, Satna (M.P.). The experiment was laid out in a randomized block design with three replicated 12 treatments viz., T1: Control, T2: 100% NPK, T3: 100% NPK +100% FYM, T4: 100% NPK + 100% VC, T5: 100% NPK + 50% FYM, T6: 100% NPK + 50% VC, T7: 100% NPK + Bioinoculant, T8: 100% NPK + 50% FYM + 50% VC, T9: 100% NPK + 50% FYM + Bioinoculant, T10: 100% NPK + 50% FYM + 50% VC + Bioinoculant, T11: 75% NPK + Bioinoculant + 100% FYM, T12: 75% NPK + Bioinoculant +100% VC. The results reveal that increase in nitrogen and Bioinoculant level had significant response on vegetative growth yield and quality of Broccoli. The treatment (T10) with 100% NPK + 50% FYM + 50% VC + Bioinoculant was found to be the best treatment among the different treatments with growth, yield and quality as well as maximum gross return for broccoli under satna condition.