Combined extensive liver resections in patients with locally advanced hepatocellular cancer – clinical cases
- 25 June 2020
- journal article
- Published by QUASAR, LLC in Research and Practical Medicine Journal
- Vol. 7 (2), 154-163
- https://doi.org/10.17709/2409-2231-2020-7-2-14
Abstract
Currently the main way of curable treatment of hepatocellular carcinomas (HCC)* is a liver resection. Candidates for surgery are patient with good score of liver function (Child-Pugh A group), without destruction of great vessels and distant metastases. Hemihepatectomy is associated with a high risk of postoperative liver failure (including portal hypertension, cirrhosis, portal vein thrombosis). This reason leads to premature failure of the operation. According to current clinical guidelines, system therapy is more suitable, despite of the lack of reliable data on its effectiveness in such clinical situations. The presented cases may support the selection of advanced hemihepatectomy as a treatment for hepatocellular cancer C stage BCLC classification.Keywords
This publication has 12 references indexed in Scilit:
- Hepatocellular carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-upAnnals of Oncology, 2018
- Asia–Pacific clinical practice guidelines on the management of hepatocellular carcinoma: a 2017 updateHepatology International, 2017
- From diagnosis to treatment of hepatocellular carcinoma: An epidemic problem for both developed and developing worldWorld Journal of Gastroenterology, 2017
- HemihepatektomieZentralblatt für Chirurgie - Zeitschrift für Allgemeine, Viszeral-, Thorax- und Gefäßchirurgie, 2016
- Sorafenib therapy for hepatocellular carcinoma with extrahepatic spread: Treatment outcome and prognostic factorsJournal of Hepatology, 2015
- Multidisciplinary Management of Hepatocellular Carcinoma in Clinical PracticeBioMed Research International, 2014
- Management of post-hepatectomy complicationsWorld Journal of Gastroenterology, 2013
- The Challenge of Prognosis and Staging for Hepatocellular CarcinomaThe Oncologist, 2010
- Outcome of partial hepatectomy for large (> 10 cm) hepatocellular carcinomaCancer, 2005
- Selection criteria for hepatic resection in patients with large hepatocellular carcinoma larger than 10 cm in diameterJournal of the American College of Surgeons, 2002