Serum N-terminal DDR1: A Novel Diagnostic Marker of Liver Fibrosis Severity
Open Access
- 25 April 2021
- journal article
- research article
- Published by Xia & He Publishing in Journal of Clinical and Translational Hepatology
- Vol. 000 (000), 000
- https://doi.org/10.14218/jcth.2021.00024
Abstract
The expression of discoidin domain receptor 1 (DDR1) is commonly up-regulated and undergoes collagen-induced ectodomain (N-terminal) shedding during the progression of liver fibrosis. This study aimed to evaluate the clinical utility of N-terminal DDR1 as a diagnostic biomarker for liver fibrosis.Keywords
This publication has 43 references indexed in Scilit:
- Discoidin Domain Receptor 1: Isoform Expression and Potential Functions in Cirrhotic Human LiverThe American Journal of Pathology, 2011
- The predictive value of FIB-4 versus FibroTest, APRI, FibroIndex and Forns index to noninvasively estimate fibrosis in hepatitis C and nonhepatitis C liver diseasesJournal of Hepatology, 2008
- Noninvasive markers of fibrosis in nonalcoholic fatty liver disease: Validating the European Liver Fibrosis Panel and exploring simple markersJournal of Hepatology, 2007
- Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinomaBritish Journal of Cancer, 2007
- Correlation of paired liver biopsies in morbidly obese patients with suspected nonalcoholic fatty liver diseaseJournal of Hepatology, 2006
- Collagen type I selectively activates ectodomain shedding of the discoidin domain receptor 1: Involvement of Src tyrosine kinaseJournal of Cellular Biochemistry, 2006
- Assessment of Liver Fibrosis: Can Serum Become the Sample of Choice?Clinical Chemistry, 2005
- Practices of Liver Biopsy in France: Results of a Prospective Nationwide SurveyJournal of Hepatology, 2000
- Cost-effectiveness of ultrasound-guided liver biopsyJournal of Hepatology, 1998
- Serum procollagen peptides and collagen type VI for the assessment of activity and degree of hepatic fibrosis in schistosomiasis and alcoholic liver diseaseJournal of Hepatology, 1992