Novel European Asiatic Clinical, Laboratory, Molecular and Pathobiological (2015-2020 CLMP) criteria for JAK2V617F trilinear polycythemia vera (PV), JAK2exon12 PV and JAK2V617F, CALR and MPL515 thrombocythemias: From Dameshek to Constantinescu-Vainchenker, Kralovics and Michiels
Open Access
- 3 April 2020
- journal article
- Published by Heighten Science Publications Corporation
- Vol. 3 (1), 001-020
- https://doi.org/10.29328/journal.ijbmr.1001011
Abstract
The Myeloproliferative Neoplasms (MPN) of trilinear polycythemia vera (PV) and megakaryocytic leukemia (ML = primary megakaryocytic granulocytic myeloproliferation: PMGM) and Essential Thrombocythemia (ET) in the studies of Dameshek and Michiels are caused by the MPN driver mutations........Keywords
This publication has 100 references indexed in Scilit:
- JAK2V617F homozygosity arises commonly and recurrently in PV and ET, but PV is characterized by expansion of a dominant homozygous subcloneBlood, 2012
- JAK2V617F mutation and allele burden are associated with distinct clinical and morphological subtypes in patients with essential thrombocythaemiaJournal of Clinical Pathology, 2012
- New mutations and pathogenesis of myeloproliferative neoplasmsBlood, 2011
- The JAK2 exon 12 mutations: A comprehensive reviewAmerican Journal of Hematology, 2011
- The JAK2 46/1 haplotype predisposes to MPL-mutated myeloproliferative neoplasmsBlood, 2010
- Bone Marrow Morphologic Features in Polycythemia Vera WithJAK2Exon 12 MutationsAmerican Journal of Clinical Pathology, 2010
- Phenotypic variability within the JAK2 V617F-positive MPD: Roles of progenitor cell and neutrophil allele burdensExperimental Hematology, 2008
- JAK2Exon 12 Mutations in Polycythemia Vera and Idiopathic ErythrocytosisThe New England Journal of Medicine, 2007
- A unique clonal JAK2 mutation leading to constitutive signalling causes polycythaemia veraNature, 2005
- Chronic Myeloproliferative Disorders in Bone Marrow BiopsiesPathology - Research and Practice, 1990