The foraging Gene and Its Behavioral Effects: Pleiotropy and Plasticity
- 3 December 2019
- journal article
- review article
- Published by Annual Reviews in Annual Review of Genetics
- Vol. 53 (1), 373-392
- https://doi.org/10.1146/annurev-genet-112618-043536
Abstract
The Drosophila melanogaster foraging ( for) gene is a well-established example of a gene with major effects on behavior and natural variation. This gene is best known for underlying the behavioral strategies of rover and sitter foraging larvae, having been mapped and named for this phenotype. Nevertheless, in the last three decades an extensive array of studies describing for’s role as a modifier of behavior in a wide range of phenotypes, in both Drosophila and other organisms, has emerged. Furthermore, recent work reveals new insights into the genetic and molecular underpinnings of how for affects these phenotypes. In this article, we discuss the history of the for gene and its role in natural variation in behavior, plasticity, and behavioral pleiotropy, with special attention to recent findings on the molecular structure and transcriptional regulation of this gene. Expected final online publication date for the Annual Review of Genetics, Volume 53 is November 23, 2019. Please see http://www.annualreviews.org/page/journal/pubdates for revised estimates.Keywords
This publication has 108 references indexed in Scilit:
- Gene–environment interplay in Drosophila melanogaster : Chronic food deprivation in early life affects adult exploratory and fitness traitsProceedings of the National Academy of Sciences of the United States of America, 2012
- foraging alters resilience/vulnerability to sleep disruption and starvation in DrosophilaProceedings of the National Academy of Sciences of the United States of America, 2012
- Critical role for protein kinase A in the acquisition of gregarious behavior in the desert locustProceedings of the National Academy of Sciences of the United States of America, 2011
- A cis-regulatory map of the Drosophila genomeNature, 2011
- The developmental transcriptome of Drosophila melanogasterNature, 2010
- Case-Control Genome-Wide Association Study of Attention-Deficit/Hyperactivity DisorderJournal of the American Academy of Child & Adolescent Psychiatry, 2010
- Molecular basis for changes in behavioral state in ant social behaviorsProceedings of the National Academy of Sciences of the United States of America, 2009
- Lethargus is a Caenorhabditis elegans sleep-like stateNature, 2008
- Natural polymorphism affecting learning and memory in DrosophilaProceedings of the National Academy of Sciences of the United States of America, 2007
- Regulation of Body Size and Behavioral State of C. elegans by Sensory Perception and the EGL-4 cGMP-Dependent Protein KinaseNeuron, 2002