Mevcut COVID-19 Aşılarının SARS-CoV-2 Varyantlarına Etkinliği Nasıl? Üçüncü Dozların Gerekliliği Hakkında Bilinmesi Gerekenler

Abstract
SARS-CoV-2 genetic variants from alpha (first detected in the UK) to delta (discovered in India this spring) to lambda (currently Argenti- na, Brazil, Chile, Colombia, Ecuador, and Peru) have been emerging and circulating the world. Also, these variants have raised concerns about the continued effectiveness of COVID-19 vaccines. In this review, influential variants cause countries to review their vaccine strat- egies, create new vaccine programs, and accelerate existing vaccine studies. The effectiveness of currently available COVID-19 vaccines on variants is discussed. It is also intended to shed light on what should be known about the necessity of third doses.