Iron‐Based Multi‐Catalysis: Eco‐Compatible Alternative for Complex Molecules Synthesis

Abstract

In the last decade, multi-catalysis has emerged as an excellent alternative to classical methods, rapidly elaborating complex organic molecules while considerably decreasing steps and waste generation. In order to further decrease costs, the application of cheaper and more available iron-based catalysts has recently arisen. Through these iron-based multi-catalytic combinations, greener transformations have been developed that generate complex organic scaffolds from simple building blocks at lower costs. In addition to the decrease in catalysts costs, it was also demonstrated that in many cases, the application of iron complexes could also lead to unique reactivity features, expanding chemist's available toolbox. All the advantages observed in terms of costs and reactivity, should make iron-based multi-catalysis one of the leading technology of the future.