Novel Amiloride Derivatives That Inhibit Bacterial Motility across Multiple Strains and Stator Types

Abstract
The bacterial flagellar motor (BFM) is a protein complex that confers motility to cells and contributes to survival and virulence. The BFM consists of stators that are ion-selective membrane protein complexes and a rotor that directly connects to a large ...
Funding Information
  • Australian Research Council (DP190100497)
  • Australian National Health and Medical Research Council (APP1100432)
  • MEXT | Japan Society for the Promotion of Science (JP18H02475, JP20K06564, JP19H05404)
  • Takeda Science Foundation
  • Commonwealth Scientific and Industrial Research Organisation (Synthetic Biology Future Science Platform Project Grant)