Long Term Follow Up of Male Breast Cancer
Open Access
- 12 September 2017
- journal article
- Vol. 86 (3), 177-180
Abstract
Male breast cancer accounts for less than 1% of breast cancers with published overall and disease free survival being lower than in females. To determine treatment and long term outcomes for male breast cancer patients in our unit. A database has been maintained for all breast cancer patients diagnosed in our unit since 1993. Patients were identified using the database and information was collated on patient demographics, tumour pathology, treatment and outcomes using the database and retrospective chart review. Patients were followed to cause of death. From 1994-2009 twenty-four cancers were diagnosed in twenty-two patients. Mean age at diagnosis was 69. Male breast cancer patients were treated using similar principles to female breast cancer. Twenty patients underwent mastectomy, two patients underwent wide local excision. No patients developed local recurrence. One patient died from their breast cancer with systemic metastases. 10-year overall survival was 22%, 10 year disease-specific survival was 80%. Other causes of death included medical co-morbidity and secondary cancers. Disease free survival in our unit is comparable to other published studies. High age at diagnosis and co-morbidity are the most important factors in determining overall outcome. Treatment pathways for male breast cancer should follow guidelines for female disease in order to optimise outcomes. Future research at national or international level is necessary to ensure the most effective treatments are implemented for male breast cancer patients.Keywords
This publication has 13 references indexed in Scilit:
- Obesity and male breast cancer: provocative parallels?BMC Medicine, 2015
- Male breast cancer according to tumor subtype and raceCancer, 2013
- Adjuvant therapy with tamoxifen compared to aromatase inhibitors for 257 male breast cancer patientsBreast Cancer Research and Treatment, 2012
- Use of Tamoxifen With Postsurgical Irradiation May Improve Survival in Estrogen and Progesterone Receptor–Positive Male Breast CancerClinical Breast Cancer, 2011
- Male breast cancerCancer Treatment Reviews, 2010
- Male Breast Cancer: A Population-Based Comparison With Female Breast CancerJournal of Clinical Oncology, 2010
- A Multicenter Study of Cancer Incidence in CHEK2 1100delC Mutation CarriersCancer Epidemiology, Biomarkers & Prevention, 2006
- Survival of Male Breast Cancer Patients: A Population-Based Study in Osaka, JapanJapanese Journal of Clinical Oncology, 2006
- Male breast cancerThe Lancet, 2006
- Breast Cancer In Men: Risk Factors with Hormonal ImplicationsAmerican Journal of Epidemiology, 1992