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ATG8ylation of proteins: A way to cope with cell stress?

Published: 20 October 2021

Abstract: The ATG8 family of proteins regulates autophagy in a variety of ways. Recently, ATG8s were demonstrated to conjugate directly to cellular proteins in a process termed “ATG8ylation,” which is amplified by mitochondrial damage and antagonized by ATG4 proteases. ATG8s may have an emerging role as small protein modifiers.
Keywords: proteins / stress / cope / proteases / conjugate / ATG8 / directly / ATG4 / autophagy / mitochondrial

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