Antiviral Potential of the Antimicrobial Drug Atovaquone against SARS-CoV-2 and Emerging Variants of Concern
- 18 October 2021
- journal article
- research article
- Published by American Chemical Society (ACS) in ACS Infectious Diseases
- Vol. 7 (11), 3034-3051
- https://doi.org/10.1021/acsinfecdis.1c00278
Abstract
No abstract availableKeywords
Funding Information
- Government of Canada (INI-147824, OV3 170632)
- Region Midtjylland (A3233)
- Det Frie Forskningsr??d (0214-00001B)
- Ontario Research Foundation (C-134-2426131-DIALLO)
- European Commission (754513)
- Aarhus Universitets Forskningsfond
- H??rslev-Fonden
- Government of Canada
- European Commission (786602)
- CHEO Research Institute
- Lundbeckfonden (R238-2016-2708, R335-2019-2138, R349-2020-419)
- Br????drene Hartman fond
This publication has 36 references indexed in Scilit:
- Specific role of mitochondrial electron transport in blood-stage Plasmodium falciparumNature, 2007
- Functional Characterization and Target Validation of Alternative Complex I of Plasmodium falciparum MitochondriaAntimicrobial Agents and Chemotherapy, 2006
- Atovaquone-proguanil for treating uncomplicated malariaEmergencias, 2005
- Randomized, Placebo‐Controlled Trial of Atovaquone/Proguanil for the Prevention ofPlasmodium falciparumorPlasmodium vivaxMalaria among Migrants to Papua, IndonesiaClinical Infectious Diseases, 2002
- Delivery of the Cre recombinase by a self-deleting lentiviral vector: Efficient gene targeting in vivoProceedings of the National Academy of Sciences of the United States of America, 2001
- dCTP levels are maintained in Plasmodium falciparum subjected to pyrimidine deficiency or excessPathogens and Global Health, 1997
- Atovaquone, a Broad Spectrum Antiparasitic Drug, Collapses Mitochondrial Membrane Potential in a Malarial ParasiteOnline Journal of Public Health Informatics, 1997
- Efficacy of atovaquone in treatment of toxoplasmosis in patients with AIDSThe Lancet, 1992
- Site of action of the antimalarial hydroxynaphthoquinone, 2-[trans-4-(4'-chlorophenyl) cyclohexyl]-3- hydroxy-1,4-naphthoquinone (566C80)Biochemical Pharmacology, 1992
- Inhibition of pyrimidine biosynthesis de novo in Plasmodium falciparum by 2-(4-t-butylcyclohexyl)-3-hydroxy-1,4-naphthoquinone in vitroMolecular and Biochemical Parasitology, 1985