Abstract
The article presents a retrospective of the main directions of research on the preservation of the health of the population and labor resources of the Siberian Federal District based on the long-term work of the Scientific Research Institute of Complex Problems of Hygiene and Occupational Diseases in Novokuznetsk. There is the ecological and hygienic definition and justification of optimal human life conditions; the development and implementation of methods for the prevention, treatment, and rehabilitation of occupational, production-related, and general diseases; planning the strategy of medical services and organizations in the management of healthcare, taking into account the peculiarities of population reproduction, the specifics of working conditions and socio-economic development of regions.

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