The article runs about the advantages of the cluster approach to the development of the region which, in contrast to others, has to set up close partner ties, the aim of which is to provide the competitiveness both of each separate participant of cluster, and the union on the whole by means of introducing innovations. The cluster union formation is of great of great importance for the economic activity of the region to be efficient, as it encourages attracting investments and producing competitive products and services on the innovative technologies basis. In the article the author draws attention to a low activity of cluster forming process in Ukraine, as in the country there are a set of challenges connected with financial resource deficiency, no confidence to the power bodies, low awareness of enterprises of clustering advantages. The cluster value as an important universal instrument capable of enhancing the economic competitiveness of individual countries (or regions) and the efficient development of the modern global economy is substantiated. On the basis of the research performed there have been defined the main tasks of making the process of clusterization to be more active in the regions of Ukraine. The article analyzes the concept of inclusive development and identifies its key points. The research made it possible to find out that there are a significant number of factors varieties in quality, intensity, force of manifestation and effect, that influence or may have an impact on inclusive local development, which is important for improving the well-being and life quality of the local population, expansion and realization its rights and opportunities. The practical significance of the results obtained is that the scientific findings, the results obtained and the suggested recommendations are a practical basis for the development and improvement of the clustering process in ensuring the economic security of the state.