Recent Advances in Hollow Gold Nanostructures for Biomedical Applications
Open Access
- 8 June 2021
- journal article
- review article
- Published by Frontiers Media SA in Frontiers in Chemistry
Abstract
The localized surface plasmon resonance of metallic nanoparticles has attracted much attention owing to its unique characteristics, including the enhancement of signals in sensors and photothermal effects. In particular, hollow gold nanostructures are highly promising for practical applications, with significant advantages being found in their material properties and structures: 1) the interaction between the outer surface plasmon mode and inner cavity mode leads to a greater resonance, allowing it to absorb near-infrared light, which can readily penetrate tissue; 2) it has anti-corrosiveness and good biocompatibility, which makes it suitable for biomedical applications; 3) it shows a reduced net density and large surface area, allowing the possibility of nanocarriers for drug delivery. In this review, we present information on the classification, characteristics, and synthetic methods of hollow gold nanostructures; discuss the recent advances in hollow gold nanostructures in biomedical applications, including biosensing, bioimaging, photothermal therapy, and drug delivery; and report on the existing challenges and prospects for hollow gold nanostructures.Keywords
Funding Information
- National Research Foundation of Korea (019R1A4A1024116 2019R1F1A1062216 2018R1D1A3B07049650)
This publication has 98 references indexed in Scilit:
- Tailoring Galvanic Replacement Reaction for the Preparation of Pt/Ag Bimetallic Hollow Nanostructures with Controlled Number of VoidsACS Nano, 2012
- Photoacoustic tomography: fundamentals, advances and prospectsContrast Media & Molecular Imaging, 2011
- Functionalized Gold Nanoparticles and Their Biomedical ApplicationsNanomaterials, 2011
- Highly uniform and reproducible surface-enhanced Raman scattering from DNA-tailorable nanoparticles with 1-nm interior gapNature Nanotechnology, 2011
- Engineering the properties of metal nanostructures via galvanic replacement reactionsMaterials Science and Engineering: R: Reports, 2010
- From Ag Nanoprisms to Triangular AuAg NanoboxesAdvanced Functional Materials, 2010
- Photoacoustic imaging of living mouse brain vasculature using hollow gold nanospheresBiomaterials, 2010
- Gold Nanocages: Synthesis, Properties, and ApplicationsAccounts of Chemical Research, 2008
- Fabrication of Cubic Nanocages and Nanoframes by Dealloying Au/Ag Alloy Nanoboxes with an Aqueous Etchant Based on Fe(NO3)3 or NH4OHNano Letters, 2007
- Facile Synthesis of Gold−Silver Nanocages with Controllable Pores on the SurfaceJournal of the American Chemical Society, 2006