Association of Early Palliative Care Use With Survival and Place of Death Among Patients With Advanced Lung Cancer Receiving Care in the Veterans Health Administration

Abstract
Palliative care has been reported to reduce patients’ physical symptom burden and improve their mood and quality of life.1 A meta-analysis has not established an association between palliative care and a survival benefit; however, the design and results of the studies included in the meta-analysis were mixed.1 A single clinical trial prespecified survival as a primary outcome,2 and only 2 others in the pooled analysis, 1 of which had a high risk of bias, reported a survival benefit.3,4