Malignancy induced haemophagocytosis of leukaemic blasts by macrophages and transformation into a multinucleated giant cells

Abstract

Haemophagocytosis is a dysregulated immune condition characterised by both inflammation and uncontrolled activation of macrophages and T-cells, which causes aberrant cytokine release, leading to cytokine storm [1] it can be primary or secondary, depending upon the etiology.