Objective: to estimate the prevalence of Complicated Surgical Wound (CSW) and to analyze the associated factors in hospitalized patients. Methodology: Epidemiological, observational, descriptive, cross-sectional, and secondary study, approved by the ethics committee, which used data previously collected from 775 patients admitted to seven public hospitals in the city of Manaus (AM) in Brazil. Clinical records, interviews, and physical examination were used as sources of information. Data from 251 patients undergoing surgery (at risk of CSW) were analyzed using the R Software for multivariate analysis with a significance level of 5%. Results: 15 patients (6%) had CSW. Male gender (p=0.016) and the presence of ecchymosis (pConclusions: A prevalence of CSW of 6% was identified in patients hospitalized in public institutions in the Brazilian Amazonas largest urban region, mainly men and with ecchymosis. The results contribute to a better understanding of the epidemiology of the condition, with important information for its prevention and early detection.