The Incidence of Esophageal Cancer in Iran: A Systematic Review and Meta-analysis
Open Access
- 26 July 2018
- journal article
- review article
- Published by Biomedical Research and Therapy in Biomedical Research and Therapy
- Vol. 5 (7), 2493-2503
- https://doi.org/10.15419/bmrat.v5i7.459
Abstract
Background: Esophageal Cancer (EC) is the eighth most common cancer in terms of incidence. Despite various studies, there is no general estimate of EC incidence in Iran. Therefore, the present study is conducted to evaluate the incidence rates of EC in Iran. Method: A systematic search was conducted on all published studies of EC incidence using Medline/PubMed, Scopus, Web of sciences, Google scholar, and four Iranian databases (Scientific Information Database, MagIran, IranMedex, and IranDoc) until November 2017. This systematic review was done according to the preferred reporting items for systematic reviews and meta-analyses (PRISMA). Result: The database, grey literature searches, and hand searching yielded 346 potentially relevant studies. A total of 22 studies were included. The results of the random effect model were demonstrated the age-standardized rate (ASR) of EC was 25.05, 95% CI (20.84 to 29.26) among males and 22.93 95 % CI (18.97-26.88) among females. Conclusion: In comparison to other geographical locations, the incidence of EC is higher in Iran. However, organized system for collecting data of cancer is required to specify the incidence and trend of EC in Iran.This publication has 30 references indexed in Scilit:
- Epidemiology of Esophageal Cancer in Japan and ChinaJournal of Epidemiology, 2013
- Extremely High Tp53 Mutation Load in Esophageal Squamous Cell Carcinoma in Golestan Province, IranPLOS ONE, 2011
- Cancer incidence in southern Iran, 1998–2002: Results of population-based cancer registryCancer Epidemiology, 2011
- Candidate Gene Association Study of Esophageal Squamous Cell Carcinoma in a High-Risk Region in IranCancer Research, 2009
- Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control studyBMJ, 2009
- Mixed-Effects Poisson Regression Models for Meta-Analysis of Follow-Up Studies with Constant or Varying DurationsThe International Journal of Biostatistics, 2009
- Cancer incidence and mortality in IranAnnals of Oncology, 2008
- Esophageal cancer: epidemiology, pathogenesis and preventionNature Clinical Practice Gastroenterology & Hepatology, 2008
- Opium, tobacco, and alcohol use in relation to oesophageal squamous cell carcinoma in a high-risk area of IranBritish Journal of Cancer, 2008
- Cancer occurrence in Ardabil: Results of a population-based Cancer Registry from IranInternational Journal of Cancer, 2003